![]() They created combinatorial antibody libraries on filamentous phage to be utilized for generating antigen specific antibodies in a matter of weeks. Gregory Winter that enabled the discovery of human antibodies for diverse applications, particularly antibody-based drugs. At the beginning of the 1990s, an in vitro antibody selection technology known as antibody phage display was developed by John McCafferty and Sir. They are the most profitable single product class, where they represent six of the top ten selling drugs. Monoclonal antibodies (mAbs) have become one of the most important classes of biopharmaceutical products, and they continue to dominate the universe of biopharmaceutical markets in terms of approval and sales. 8Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.7Australian Research Council Training Centre for Biopharmaceutical Innovation, The University of Queensland, Brisbane, QLD, Australia.6Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, Australia.5Department of Medical Laboratory Technology, University of Tabuk, Tabuk, Saudi Arabia.4College of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia.3Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Taif University, Taif, Saudi Arabia. ![]() 2Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.1Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia. ![]() Alsaab 3, Ahmad Bakur Mahmoud 4, Almohanad A. ![]()
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